Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 47, Issue 6, Pages 1269-1274Publisher
WILEY
DOI: 10.1002/jhet.464
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A novel class of coumarin-thiazole conjugated systems (1-31) were synthesized by Hantzsch condensation between alpha-bromo-3-acetyl coumarin and several thiosemicarbazone intermediates. This scaffold was also evaluated for selective antibacterial activity against 20 isolates of H. pylori clinical strains, including four metronidazole resistant ones.
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