4.4 Article

A Simple and Practical Method for the Synthesis of 2-Amino-5,6-dihydro-5,7-diarylquinazolin-4-ols

Journal

JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 46, Issue 6, Pages 1346-1348

Publisher

WILEY
DOI: 10.1002/jhet.229

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Funding

  1. Cavinkare Research Centre, Chennai

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We report an efficient and new method of synthesis of 2-amino-5,6-dihydro-5,7-diarylquinazolin-4-ols by the reaction of substituted cyclohexenones with guanidine hydrochloride in presence of NaOEt. The reactions are with 50-72% yield. All the synthesized compounds are characterized using IR, NMR and CHN analysis.

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