4.4 Article

One-Pot Three-Component Synthesis of Dihydrobenzo- and Naphtho[e]-1,3-oxazines in Water

Journal

JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 46, Issue 5, Pages 1003-1006

Publisher

WILEY
DOI: 10.1002/jhet.147

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Funding

  1. CSIR, India

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A simple, green and efficient method has been developed for the synthesis of biologically and materially important dihydrobenzo/naphtho[e]-1,3-oxazines in good to excellent yields through a Mannich-type condensation cyclization reaction of aromatic alcohols with HCHO and primary amines in aqueous media at ambient temperature.

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