Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 45, Issue 4, Pages 1077-1081Publisher
WILEY-BLACKWELL
DOI: 10.1002/jhet.5570450420
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An advantageous ligand-free protocol for Suzuki couplings is described. The synthetic procedure entails microwave irradiation for the reduction of the reaction times and the use of silica cartridges for the purification. Dihalo-pyrimidine structures, interesting scaffolds in medicinal chemistry, were chosen as test compounds.
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