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Gastric GI stromal tumors (GISTs): The role of surgery in the era of targeted therapy
MC Heinrich et al.
JOURNAL OF SURGICAL ONCOLOGY (2005)
Bevacizurnab in combination with fluorouracil and leucovorin: An active regimen for first-line metastatic colorectal cancer
HI Hurwitz et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
DB Agus et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies
NL Spector et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Mutant V599EB-RAF regulates growth and vascular development of malignant melanoma tumors
A Sharma et al.
CANCER RESEARCH (2005)
State-of-the art therapy for gastrointestinal stromal tumors
CD Blanke et al.
CANCER INVESTIGATION (2005)
Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity
M Debiec-Rychter et al.
JOURNAL OF PATHOLOGY (2004)
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial
J Verweij et al.
LANCET (2004)
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
DH Johnson et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Imatinib mesylate (STI-571 Glivec®, Gleevec™) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target:: Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study
J Verweij et al.
EUROPEAN JOURNAL OF CANCER (2003)
The role of functional and molecular imaging in cancer drug discovery and development
BM Seddon et al.
BRITISH JOURNAL OF RADIOLOGY (2003)
How much gets there and what does it do?: The need for better pharmacokinetic and pharmacodynamic endpoints in contemporary drug discovery and development
P Workman
CURRENT PHARMACEUTICAL DESIGN (2003)
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study
M Talpaz et al.
BLOOD (2002)
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
DJ Slamon et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Synergistic activity of the new ABL-specific tyrosine kinase inhibitor ST1571 and chemotherapeutic drugs on BCR-ABL-positive chronic myelogenous leukemia cells
J Topaly et al.
LEUKEMIA (2001)