Journal
JOURNAL OF HEART AND LUNG TRANSPLANTATION
Volume 31, Issue 9, Pages 1037-1040Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.healun.2012.05.008
Keywords
foscarnet; lung transplantation; cytomegalovirus; treatment; adverse event; precipitation; crystal nephropathy
Funding
- Fondation Nuovo-Soldati
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We present the case of a lung transplant recipient with disseminated crystal precipitation, and granulomatous and fibrinous inflammation after therapy with foscarnet (Foscavir; AstraZeneca, Zug, Switzerland) for recurring ganciclovir-resistant cytomegalovirus (CMV) reactivation. This is the first description of systemic crystal precipitation and granulomatous inflammation associated with foscarnet therapy with predominant involvement of the heart, kidneys and lungs. J Heart Lung Transplant 2012;31:1037-40 (C) 2012 International Society for Heart and Lung Transplantation. All rights reserved.
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