Related references
Note: Only part of the references are listed.Inhibitory effect of BIBN4096BS, CGRP8-37, a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery
L. Edvinsson et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Potent, orally bioavailable calcitonin gene-related peptide receptor antagonists for the treatment of migraine:: Discovery of N-[(3R,6S)-6-(2,3-Difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide (MK-0974)
Daniel V. Paone et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Allodynia in different forms of migraine
C. Lovati et al.
NEUROLOGICAL SCIENCES (2007)
Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion
Zhongming Zhang et al.
JOURNAL OF NEUROSCIENCE (2007)
Recent advances in understanding migraine mechanisms, molecules and therapeutics
Peter J. Goadsby
TRENDS IN MOLECULAR MEDICINE (2007)
Intravital microscopy on a closed cranial window in mice: a model to study trigeminovascular mechanisms involved in migraine
S. Gupta et al.
CEPHALALGIA (2006)
Characterisation of CGRP receptors in the human isolated middle meningeal artery
Saurabh Gupta et al.
LIFE SCIENCES (2006)
Subcutaneous sumatriptan provides symptomatic relief at any pain intensity or time during the migraine attack
M Linde et al.
CEPHALALGIA (2006)
GPCR modulation by RAMPS
DL Hay et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Development of human calcitonin gene-related peptide (CGRP) receptor antagonists.: 1.: Potent and selective small molecule CGRP antagonists.: 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)piperazine:: The first CGRP antagonist for clinical trials in acute migraine
K Rudolf et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Triptan-induced contractile (5-HT1B receptor) responses in human cerebral and coronary arteries:: relationship to clinical effect
L Edvinsson et al.
CLINICAL SCIENCE (2005)
A positron emission tomographic study in spontaneous migraine
SK Afridi et al.
ARCHIVES OF NEUROLOGY (2005)
Presence and function of the calcitonin gene-related peptide receptor on rat pial arteries investigated in vitro and in vivo
KA Petersen et al.
CEPHALALGIA (2005)
Neurobiology in primary headaches
L Edvinsson et al.
BRAIN RESEARCH REVIEWS (2005)
Investigation of the species selectivity of a nonpeptide CGRP receptor antagonist using a novel pharmacodynamic assay
JC Hershey et al.
REGULATORY PEPTIDES (2005)
BIBN4096BS antagonizes human α-calcitonin gene related peptide-induced headache and extracerebral artery dilatation
KA Petersen et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack
G Juhasz et al.
CEPHALALGIA (2005)
The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers
KA Petersen et al.
CEPHALALGIA (2005)
Migraine, allodynia, sensitisation and all of that...
PJ Goadsby
EUROPEAN NEUROLOGY (2005)
Calcitonin gene-related peptide antagonists as treatments of migraine and other primary headaches
PJ Goadsby
DRUGS (2005)
Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT1B/1D receptor agonists
D Levy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Calcitonin gene-related peptide receptor antagonist BIBN4096BS for the acute treatment of migraine
J Olesen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Clinical recognition of allodynia in migraine
NT Mathew et al.
NEUROLOGY (2004)
Calcitonin gene-related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat
RJ Storer et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Safety, tolerability and pharmacokinetics of BIBN4096BS, the first selective small molecule calcitonin gene-related peptide receptor antagonist, following single intravenous administration in healthy volunteers
M Iovino et al.
CEPHALALGIA (2004)
Blockade of CGRP receptors in the intracranial vasculature: a new target in the treatment of headache
L Edvinsson
CEPHALALGIA (2004)
Analgesic triptan action in an animal model of intracranial pain: A race against the development of central sensitization
R Burstein et al.
ANNALS OF NEUROLOGY (2004)
Inhibitory effect of BIBN4096BS on cephalic vasodilatation induced by CGRP or transcranial electrical stimulation in the rat
KA Petersen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
NO-induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release
G Juhasz et al.
PAIN (2003)
In-depth characterization of CGRP receptors in human intracranial arteries
I Jansen-Olesen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
Spreading and synchronous depressions of cortical activity in acutely injured human brain
AJ Strong et al.
STROKE (2002)
An immunocytochemical investigation of human trigeminal nucleus caudalis:: CGRP, substance P and 5-HT1D-receptor immunoreactivities are expressed by trigeminal sensory fibres
D Smith et al.
CEPHALALGIA (2002)
Immunohistochemical localization of calcitonin receptor-like receptor and receptor activity-modifying proteins in the human cerebral vasculature
KR Oliver et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model
H Bolay et al.
NATURE MEDICINE (2002)
Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries and in SK-N-MC cells
L Edvinsson et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Oral triptans (serotonin 5-HT1B/1D agonists) in acute migraine treatment:: a meta-analysis of 53 trials
MD Ferrari et al.
LANCET (2001)
5-HT1B and 5-HT1D receptors in the human trigeminal ganglion:: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase
MY Hou et al.
BRAIN RESEARCH (2001)
Neuronal messengers in the human cerebral circulation
S Gulbenkian et al.
PEPTIDES (2001)
Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels
AM VanDenBrink et al.
NEUROLOGY (2000)
CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors
BN Evans et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Positive inotropy mediated via CGRP receptors in isolated human myocardial trabeculae
OS Opgaard et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
H Doods et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)