Journal
JOURNAL OF HAZARDOUS MATERIALS
Volume 254, Issue -, Pages 336-344Publisher
ELSEVIER
DOI: 10.1016/j.jhazmat.2013.04.005
Keywords
Silver nanoparticles; Silver nitrate; Toxicity; Gene expression; Enchytraeus albidus
Categories
Funding
- FEDER through COMPETE Programa Operacional Factores de Competitividade
- National funding through FCT-Fundacao para a Ciencia e Tecnologia [NANOkA FCOMP-01-0124-FEDER-008944, FCT PTDC/BIA-BEC/103716/2008, SFRH/BD/63261/2009]
- EU-FP7 MARINA [263215]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/63261/2009, PTDC/BIA-BEC/103716/2008] Funding Source: FCT
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Silver has antimicrobial properties and silver nanoparticles (Ag-NPs) have been some of the most widely used NPs. Information regarding their effects is still insufficient, in particular for soil dwelling organisms. The standard soil Oligochaete Enchytraeus albidus was used to study the effects of Ag in soils, using differential gene expression (microarray) and population (survival, reproduction) response to Ag-Ns (PVP coated) and AgNO3. Results showed higher toxicity of AgNO3 (EC50 < 50 mg/kg) compared to toxicity of Ag-NPs (EC50 = 225 mg/kg). Based on the biological and material identity, the difference in toxicity between Ag-NPs and AgNO3 could possibly be explained by a release of Ag+ ions from the particles or by a slower uptake of Ag-NPs. The indications were that the responses to Ag-NPs reflect an effect of Ag ions and Ag-NPs given the extent of similar/dissimilar genes activated: The particles characterization supports this deduction as there were limited free ions measured in soil extracts, maybe related to little oxidation and/or complexation in the soil matrix. The possibility that gene differences were due to different levels of biological impact (i.e. physiological responses) should not be excluded. Testing of Ag-NPs seem to require longer exposure period to be comparable in terms of effect/risk assessment with other chemicals. (C) 2013 Elsevier B.V. All rights reserved.
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