4.6 Article

A Grid-Enabled Gateway for Biomedical Data Analysis

Journal

JOURNAL OF GRID COMPUTING
Volume 10, Issue 4, Pages 725-742

Publisher

SPRINGER
DOI: 10.1007/s10723-012-9233-4

Keywords

Scientific gateway; Grid computing; Biomedical research; E-science; Grid user interface; Grid web portal

Funding

  1. AMC ICT innovation fund
  2. BiG Grid programme
  3. Nederlandse Organisatie voor Wetenschappelijk Onderzoek (Netherlands Organisation for Scientific Research, NWO)
  4. COMMIT project e-Biobanking with imaging for healthcare

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Biomedical researchers can leverage Grid computing technology to address their increasing demands for data- and compute-intensive data analysis. However, usage of existing Grid infrastructures remains difficult for them. The e-infrastructure for biomedical science (e-BioInfra) is a platform with services that shield middleware complexities, in particular workflow management and monitoring. These services can be invoked from a web-based interface, called e-BioInfra Gateway, to perform large scale data analysis experiments, such that the biomedical researchers can focus on their own research problems. The gateway was designed to simplify usage both by biomedical researchers and e-BioInfra administrators, and to support straightforward extensions with new data analysis methods. In this paper we present the architecture and implementation of the gateway, also showing statistics for its usage. We also share lessons learned during the gateway development and operation. The gateway is currently used in several biomedical research projects and in teaching medical students the principles of data analysis.

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