Journal
OPTICS EXPRESS
Volume 23, Issue 22, Pages 28593-28604Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.23.028593
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A multi-analyte biosensing platform with ultra-high resolution (= 0.2 ng/mL),-which is appropriate for the detection in the human serum of a wide range of biomarkers, e.g. those allowing the lung cancer early diagnosis, has been designed. The platform is based on a new configuration of planar ring resonator. The very strong light-matter interaction enabled by the micro-cavity allows a record limit-of-detection of 0.06 pg/mm(2), five times better than the state-of-the-art. The device with footprint = 2,200 mu m(2) for each ring, due to its features, has the potential to be integrated in lab-on-chip microsystems for large-scale screenings of people with high risk of developing cancer. (C) 2015 Optical Society of America
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