Journal
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
Volume 28, Issue 1, Pages 19-26Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0891988714541874
Keywords
behavioral variant frontotemporal dementia; Alzheimer disease; activities of daily living; cognition; functional status; executive functions
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Funding
- Sao Paulo Research Foundation (FAPESP) [11/04804-1]
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [11/04804-1] Funding Source: FAPESP
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Background: There is limited information about the functional profile of behavioral variant frontotemporal dementia (bvFTD). Objective: To compare direct and indirect assessments of activities of daily living (ADLs) in bvFTD and Alzheimer disease (AD) and their relationship with cognitive performance. Methods: In all, 20 patients with bvFTD, 30 patients with AD, and 34 normal controls (NCs), matched for age, education, and severity of dementia, completed the Direct Assessment of Functional Performance (DAFS-BR) and usual cognitive measures. The Disability Assessment for Dementia (DAD) was completed by caregivers. Results: In DAFS-BR, patients with bvFTD and AD had similar performance but lower than NCs. In DAD, there were no significant differences for effective performance, but patients with bvFTD had lower scores for initiation and planning/organization. Patients with bvFTD were less impaired than AD in cognition. Conclusion: Functional changes in bvFTD seem to be better documented by indirect measures.
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