Journal
OPTICS EXPRESS
Volume 23, Issue 13, Pages 17156-17168Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.23.017156
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Funding
- Japan Society for the Promotion of Science [25286034]
- University of Tsukuba Nanotechnology Platform
- Grants-in-Aid for Scientific Research [25286034] Funding Source: KAKEN
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A microfabricated directional coupler (DC) was used for the detection of DNA conjugated with quantum dots. Output optical signals from DCs of a wide range of device lengths correspond well to theoretical and simulation results. Even 20 mu m-long DC devices could detect changes in the output optical intensity by monitoring the near-field pattern using a CCD camera. The signal was enhanced 60 x using a 1500 mu m-long DC device. For large cladding refractive-index changes between air and water, the normalized signal changed cyclically several times between 0 and 1. The results suggest that the DC can be the basis for miniaturized two-dimensionally integrated biochemical sensors. (C) 2015 Optical Society of America
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