Journal
JOURNAL OF GENERAL VIROLOGY
Volume 95, Issue -, Pages 905-909Publisher
MICROBIOLOGY SOC
DOI: 10.1099/vir.0.062349-0
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Funding
- European Union DG Research through the program ANTIGONE [278976]
- German Centre for Infection Research (DZIF)
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A novel reovirus, designated Cimodo virus (CMDV), was isolated from mosquitoes collected in a rainforest region in Cote d'Ivoire. The entire genome comprised 24 835 bp divided into 12 segments ranging from 585 to 4080 bp. The icosahedral non-enveloped virions were 80 nm in diameter.. Eight major viral proteins of about 150, 135, 120, 80, 66, 59, 42 and 30 kDa were identified and seven proteins were mapped to the corresponding genome segments by liquid chromatography mass spectrometry. Predicted protein genes diverged by >77% encoded amino acids from their closest reovirus relatives. The deep phylogenetic branching suggests that CMDV defines an as-yet-unidentified genus within the subfamily Spinareovirinae.
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