Journal
JOURNAL OF GENERAL VIROLOGY
Volume 96, Issue -, Pages 106-114Publisher
MICROBIOLOGY SOC
DOI: 10.1099/vir.0.069120-0
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Group A rotaviruses (RVAs) are enteric pathogens with well-documented zoonotic transmissions to humans. The segmented genome of the virus enables reassortment events which might alter host susceptibility and/or disease course. Genetic analysis of rotavirus in dogs has so far only revealed RVAs with the VP7 and VP4 genome constellation G3P[3]. RVA G3P[3] have also been found in cats, humans, monkeys and bats. In the present study, we described an unusual RVA of genotype G8P[1] which was isolated from an asymptomatically infected young dog. The dog did not show signs of diarrhoea. Analysis of full-length segments of VP2, VP6 and VP7 as well as NSP1 NSP5 revealed a typical bovine-like genotype constellation G8 P[1]-I2-Rx-C2-Mx-A3-N2-T6-E2-H3. Phylogenetic analysis supported the hypothesis of an interspecies transmission from a bovine/artiodactyl species or from humans to the young dog. The isolate was likely to represent a multiple reassortant virus.
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