Journal
JOURNAL OF GENERAL VIROLOGY
Volume 92, Issue -, Pages 2674-2678Publisher
MICROBIOLOGY SOC
DOI: 10.1099/vir.0.034702-0
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Funding
- Samuel Roberts Noble Foundation
- National Science Foundation [EF-067108]
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The family Endornaviridae contains several members from diverse hosts, including plants, fungi and oomycetes. They are found as large dsRNA elements with a nick in the coding strand. All members encode a conserved RNA-dependent RNA polymerase, but no other domain that is conserved among all members. Based on the conserved domain database comparison the various domains have different origins, indicating a highly modular evolutionary history. In some cases, domains with similar putative functions are found that are derived from different protein families, indicating convergent evolution for a required function.
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