Journal
JOURNAL OF GENERAL PHYSIOLOGY
Volume 139, Issue 4, Pages 261-272Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1085/jgp.201210773
Keywords
-
Categories
Funding
- U.S. National Institutes of Health [GM 086167]
- Muscular Dystrophy Association
Ask authors/readers for more resources
In skeletal muscle fibers, action potentials elicit contractions by releasing calcium ions (Ca2+) from the sarcoplasmic reticulum. Experiments on individual mouse muscle fibers micro-injected with a rapidly responding fluorescent Ca2+ indicator dye reveal that the amount of Ca2+ released is three-to fourfold larger in fast-twitch fibers than in slow-twitch fibers, and the proportion of the released Ca2+ that binds to troponin to activate contraction is substantially smaller.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available