Journal
JOURNAL OF FORENSIC SCIENCES
Volume 54, Issue 2, Pages 289-304Publisher
WILEY
DOI: 10.1111/j.1556-4029.2008.00953.x
Keywords
forensic science; mitochondrial genome; domestic dog; control region; single nucleotide polymorphism; haplotype
Categories
Ask authors/readers for more resources
Dog hair is often found at crime scenes either due to the dog's involvement in the crime or secondary transfer. As little nuclear DNA is present in shed hair, a 1000 base pair fragment of the mitochondrial control region (mtCR) from 552 dogs was assessed for forensically useful sequence variation. Through pairwise alignment to a standard reference sequence, existing haplotypes were further described and 36 new haplotypes and 24 new single nucleotide polymorphisms were identified. The probability of exclusion was found to be 0.957. Breeds were found to have similar sequences, although not identical. No genetic basis was found for grouping dogs by either purebred or mixed or geographic location within the continental United States. Our research demonstrates that the domestic dog mtCR has not been thoroughly surveyed for sequence variation and that a single database comprised of purebred and mixed breed dogs is sufficient for the continental United States.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available