Journal
JOURNAL OF FLUORINE CHEMISTRY
Volume 161, Issue -, Pages 128-133Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2014.01.020
Keywords
Trifluoromethylation; Enol acetates; Synthetic methods; alpha-CF3 ketone; Radical addition
Categories
Funding
- National Natural Science Foundation of China (NSFC) [21176039, 20923006]
Ask authors/readers for more resources
An efficient method for the Cu(I)-catalyzed synthesis of a-trifluoromethyl ketones via the addition of CF3 to aryl(heteroaryl) enol acetates by using the readily available CF3SO2Na (Langlois reagent) has been developed. The reaction is experimentally simple and carried out at room temperature, providing good to excellent yields with wide functional group tolerance. (C) 2014 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available