Journal
JOURNAL OF FLUORINE CHEMISTRY
Volume 135, Issue -, Pages 87-90Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2011.09.001
Keywords
Hexafluoroisopropanol; Recyclable; Indole; Bis-indolyl methane
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Funding
- Islamic Azad University, Ayatollah Amoli Branch
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A simple inexpensive, environmentally friendly and efficient route for the synthesis of bis-indolyl methanes derivatives by the reaction of indole or N-methyl indole with aldehydes using hexafluoroisopropanol as a solvent is described. The solvent (HFIP) can be readily separated from reaction products and recovered in excellent purity for direct reuse. (C) 2011 B.V. All rights reserved.
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