4.3 Article

Decarboxylation of fluorosulfones for the preparation fluoroalkylidene precursors

Journal

JOURNAL OF FLUORINE CHEMISTRY
Volume 134, Issue -, Pages 128-135

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2011.03.005

Keywords

Fluorosulfones; Benzothiazole; Julia-Kocienski reaction; Krapcho; Decarboxylation

Funding

  1. European programme Innovative Synthesis, Culture, and Entrepreneurship in Chemistry (ISCE-Chem)
  2. European Community (INTERREG IVa, trans-Channel) [4061]
  3. Region Basse-Normandie

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The synthesis of fluorosulfones by alkylation of fluoroacetate derivatives is reported. Their decarboxylation reaction under Krapcho conditions is a convenient process to prepare fluorosulfones as reagents for fluoroalkene synthesis. (C) 2011 Elsevier B.V. All rights reserved.

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