4.3 Article

Transition metal-catalyzed cyclopropanation of alkenes in fluorinated alcohols

Journal

JOURNAL OF FLUORINE CHEMISTRY
Volume 132, Issue 10, Pages 811-814

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2011.05.018

Keywords

Cyclopropane; Fluorine; Copper; Ethyl diazoacetate

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The system hexafluoroisopropanol/ethyl diazoacetate/Cu(OTf)(2) is efficient for the cyclopropanation reaction. The process is experimentally simple, and efficient with various olefins in particular terminal, disubstituted double bonds. (C) 2011 Elsevier B.V. All rights reserved.

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