Journal
JOURNAL OF FLUORESCENCE
Volume 22, Issue 1, Pages 403-408Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10895-011-0973-5
Keywords
Quantum dots; Zinc sulphide; Doping; Chitosan; Bio-labeling
Funding
- National Nanotechnology Center, National Science & Technology Development Agency (NSTDA), Ministry of Science and Technology (MOST), Thailand
- Centre of Excellence in Nanotechnology at the Asian Institute of Technology, Thailand
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A novel biocompatible chitosan passivated manganese doped zinc sulfide (Mn doped ZnS) nanophosphor has been synthesized through a simple aqueous precipitation reaction. Upon excitation with ultraviolet light, the quantum dots (QDs) emit an orange luminescence peaking at 590 nm, which is visible to the naked eye. These chitosan coated Mn doped ZnS QDs can have potential applications in bio-labeling, particularly in fluorescence-based imaging. One of the envisioned applications of these QDs is in improving the conventional, organic dye-reliant Fluorescence in situ Hybridization (FISH) technique, a widely used method for microbial detection. Here we demonstrate that the chitosan-capped Mn doped ZnS QDs are suitable for this purpose.
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