4.4 Article

Cilostazol Determination by the Enhancement of the Green Emission of Tb3+ Optical Sensor

Journal

JOURNAL OF FLUORESCENCE
Volume 21, Issue 6, Pages 2229-2235

Publisher

SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10895-011-0927-y

Keywords

Cilostazol; Terbium(III); Enhancing; Luminescence; Optical sensor

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The efficiency of excited-state interaction between Tb3+ and the industrial product Cilostazol (CIL) has been studied in different solvents. High luminescence intensity peak at 545 nm of terbium complex in acetonitrile was obtained. The photophysical properties of the green emissive Tb3+ complex have been elucidated, the terbium was used as optical sensor for the assessment of CIL in the pharmaceutical tablets and body fluids at pH 3.1 and lambda(ex) = 320 nm with a concentration range 1.0 x 10(-9)-1.0 x 10(-6) mol L-1 of CIL, correlation coefficient of 0.998 and detection limit of 7.5 x 10(-10) mol L-1.

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