4.5 Article

Gross and histopathological characteristics of two lipomas and a neurofibrosarcoma detected in aquacultured southern bluefin tuna, Thunnus maccoyii (Castelnau), in South Australia

Journal

JOURNAL OF FISH DISEASES
Volume 31, Issue 4, Pages 241-247

Publisher

BLACKWELL PUBLISHING
DOI: 10.1111/j.1365-2761.2007.00863.x

Keywords

immunohistochemistry; lipoma; neoplasm; neurofibrosarcoma; schwannoma; tuna

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Three visible lesions were examined from two specimens of southern bluefin tuna. The lesions were examined grossly and two were identified as lipomas, the third bore similarities to a schwannoma. Histopathology confirmed that two consisted of mature adipocytes consistent with a diagnosis of lipoma. The third lesion consisted of spindle cells in Antoni A and B patterns and was tentatively diagnosed as a malignant schwannoma. Immunohistochemistry identified both S100 and glial fibrillary acid protein expression within the lesion, which, together with the histopathological appearance, is consistent with a diagnosis of neurofibrosarcoma.

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