Journal
JOURNAL OF FELINE MEDICINE AND SURGERY
Volume 13, Issue 2, Pages 120-124Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1016/j.jfms.2010.09.001
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- RCVS Trust
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This paper documents the first reported case of fucosidosis in a cat. The cat presented with signs of forebrain and cerebellar dysfunction and a magnetic resonance imaging scan of the brain suggested a degenerative or metabolic disease process. A fine needle aspirate of grossly normal lymph nodes revealed vacuolated lymphocytes and a renal biopsy of an irregular shaped kidney identified vacuolated tubular epithelial cells. A white cell lysosomal enzyme screen revealed negligible a-fucosidase activity. Fucosidosis should be considered in the differential diagnosis of young cats with cerebellar dysfunction and must be added to the list of lysosomal storage diseases affecting the cat. (C) 2010 ISFM and AAFP. Published by Elsevier Ltd. All rights reserved.
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