Journal
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
Volume 21, Issue 5, Pages 450-463Publisher
SPRINGERNATURE
DOI: 10.1038/jes.2011.4
Keywords
nanoparticles; exposure modeling; coagulation; source-receptor; modifying factors
Funding
- EU [NMP4-LA-2009-211464]
- Dutch Ministry of Social Affaires and Employment
- Occupational Safety and Health Advisory Boards for the Industry, Teaching and Research
- Ministry of Science, Technology and Innovation in Denmark
Ask authors/readers for more resources
As workplace air measurements of manufactured nanoparticles are relatively expensive to conduct, models can be helpful for a first tier assessment of exposure. A conceptual model was developed to give a framework for such models. The basis for the model is an analysis of the fate and underlying mechanisms of nanoparticles emitted by a source during transport to a receptor. Four source domains are distinguished; that is, production, handling of bulk product, dispersion of ready-to-use nanoproducts, fracturing and abrasion of end products. These domains represent different generation mechanisms that determine particle emission characteristics; for example, emission rate, particle size distribution, and source location. During transport, homogeneous coagulation, scavenging, and surface deposition will determine the fate of the particles and cause changes in both particle size distributions and number concentrations. The degree of impact of these processes will be determined by a variety of factors including the concentration and size mode of the emitted nanoparticles and background aerosols, source to receptor distance, and ventilation characteristics. The second part of the paper focuses on to what extent the conceptual model could be fit into an existing mechanistic predictive model for conventional exposures. The model should be seen as a framework for characterization of exposure to (manufactured) nanoparticles and future exposure modeling. Journal of Exposure Science and Environmental Epidemiology (2011) 21, 450-463; doi: 10.1038/jes.2011.4; published online 2 March 2011
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available