Journal
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 207, Issue 2, Pages 269-272Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1084/jem.20100105
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A population of cells that expresses the NK cell receptor NKp46 and produces interleukin (IL)-22 have recently attracted considerable attention. The identity of these cells is still the subject of speculation, being variably defined as a novel NK cell subset or as a population containing conventional NK (cNK) cell precursors. In this issue, two studies shed light on this conundrum, demonstrating that NKp46(+) IL-22(+) cells and cNK cells belong to distinct lineages.
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