Related references
Note: Only part of the references are listed.COSMIC: exploring the world's knowledge of somatic mutations in human cancer
Simon A. Forbes et al.
NUCLEIC ACIDS RESEARCH (2015)
Negative feedback at kinetochores underlies a responsive spindle checkpoint signal
Wilco Nijenhuis et al.
NATURE CELL BIOLOGY (2014)
Characterization of novel MPS1 inhibitors with preclinical anticancer activity
M. Jemaa et al.
CELL DEATH AND DIFFERENTIATION (2013)
Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation
Mathijs Vleugel et al.
JOURNAL OF CELL BIOLOGY (2013)
Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3,2-c]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)
Sebastien Naud et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs
Bakhos A. Tannous et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
Seung Woo Cho et al.
NATURE BIOTECHNOLOGY (2013)
The quest to overcome resistance to EGFR-targeted therapies in cancer
Curtis R. Chong et al.
NATURE MEDICINE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
The MPS1 Family of Protein Kinases
Xuedong Liu et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors
D. Vijay Kumar et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint
Lindsey A. Shepperd et al.
CURRENT BIOLOGY (2012)
Phosphoregulation of Spc105 by Mps1 and PP1 Regulates Bub1 Localization to Kinetochores
Nitobe London et al.
CURRENT BIOLOGY (2012)
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components
Yuya Yamagishi et al.
NATURE CELL BIOLOGY (2012)
Using transcriptome sequencing to identify mechanisms of drug action and resistance
Sarah A. Wacker et al.
NATURE CHEMICAL BIOLOGY (2012)
Mechanisms of drug resistance in kinases
Rina Barouch-Bentov et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2011)
Characterization of the Cellular and Antitumor Effects of MPI-0479605, a Small-Molecule Inhibitor of the Mitotic Kinase Mps1
Keith D. Tardif et al.
MOLECULAR CANCER THERAPEUTICS (2011)
High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells
Jewel Daniel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Drug-Resistant Aurora A Mutants for Cellular Target Validation of the Small Molecule Kinase Inhibitors MLN8054 and MLN8237
Dominic A. Sloane et al.
ACS CHEMICAL BIOLOGY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Biophysical and X-ray Crystallographic Analysis of Mps1 Kinase Inhibitor Complexes
Matthew L. H. Chu et al.
BIOCHEMISTRY (2010)
Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase
Riccardo Colombo et al.
CANCER RESEARCH (2010)
A chemical tool box defines mitotic and interphase roles for Mps1 kinase
Weijie Lan et al.
JOURNAL OF CELL BIOLOGY (2010)
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
Stefano Santaguida et al.
JOURNAL OF CELL BIOLOGY (2010)
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex
Laura Hewitt et al.
JOURNAL OF CELL BIOLOGY (2010)
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function
Nicholas Kwiatkowski et al.
NATURE CHEMICAL BIOLOGY (2010)
Discovery and Exploitation of Inhibitor-resistant Aurora and Polo Kinase Mutants for the Analysis of Mitotic Networks
Paul J. Scutt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells
Aniek Janssen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Molecular basis of drug resistance in Aurora kinases
Fiona Girdler et al.
CHEMISTRY & BIOLOGY (2008)
Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells
Anna Morena D'Alise et al.
MOLECULAR CANCER THERAPEUTICS (2008)
A helix scaffold for the assembly of active protein kinases
Alexandr P. Kornev et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia
Ellen Weisberg et al.
NATURE REVIEWS CANCER (2007)
The spindle-assembly checkpoint in space and time
Andrea Musacchio et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Rational design of inhibitors that bind to inactive kinase conformations
Y Liu et al.
NATURE CHEMICAL BIOLOGY (2006)
Ablation of the spindle assembly checkpoint by a compound targeting Mps1
M Schmidt et al.
EMBO REPORTS (2005)
The Aurora A and Aurora B protein kinases - A single amino acid difference controls intrinsic activity and activation by TPX2
PA Eyers et al.
CELL CYCLE (2005)
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication
VM Stucke et al.
EMBO JOURNAL (2002)
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
ME Gorre et al.
SCIENCE (2001)
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint
A Abrieu et al.
CELL (2001)
Share Paper
