Related references
Note: Only part of the references are listed.Quantitative visualization of DNA G-quadruplex structures in human cells
Giulia Biffi et al.
NATURE CHEMISTRY (2013)
Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death
Laurent R. Gauthier et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells
Xiao-Fen Lai et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2012)
Inhibition of telomerase activity by HDV ribozyme in cancers
Yingying Lu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy
E. Salvati et al.
ONCOGENE (2010)
A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel
Steven A. Titus et al.
ANALYTICAL BIOCHEMISTRY (2009)
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway
Angela Rizzo et al.
NUCLEIC ACIDS RESEARCH (2009)
Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures
Thomas P. Garner et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
G-Quadruplex Ligand RHPS4 Potentiates the Antitumor Activity of Camptothecins in Preclinical Models of Solid Tumors
Carlo Leonetti et al.
CLINICAL CANCER RESEARCH (2008)
Antitumor polycyclic acridines. 20. search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: Telomere-targeted agents
Mai-Kim Cheng et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect
Erica Salvati et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism
P. Phatak et al.
BRITISH JOURNAL OF CANCER (2007)
Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge
Elizabeth W. White et al.
BIOPHYSICAL CHEMISTRY (2007)
Synthetic strategies to a telomere-targeted pentacyclic heteroaromatic salt
Ian Hutchinson et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2007)
Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution
Anh Tuan Phan et al.
NUCLEIC ACIDS RESEARCH (2006)
Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin:: in vitro and in vivo studies in acute leukemia
T. Tauchi et al.
ONCOGENE (2006)
Structure of the human telomere in K+ solution:: An intramolecular (3+1) G-quadruplex scaffold
Kim Ngoc Luu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
The Apollo 5′ exonuclease functions together with TRF2 to protect telomeres from DNA repair
Christelle Lenain et al.
CURRENT BIOLOGY (2006)
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution
Attila Ambrus et al.
NUCLEIC ACIDS RESEARCH (2006)
DNA architecture: from G to Z
Anh Tuan Phan et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2006)
Antitumor polycyclic acridines. 17. Synthesis and pharmaceutical profiles of pentacyclic acridinium salts designed to destabilize telomeric integrity
JC Cookson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end
D Hockemeyer et al.
EMBO JOURNAL (2005)
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function
AM Burger et al.
CANCER RESEARCH (2005)
Prevalence of quadruplexes in the human genome
JL Huppert et al.
NUCLEIC ACIDS RESEARCH (2005)
Beginning to understand the end of the chromosome
TR Cech
CELL (2004)
Synthesis and properties of bioactive 2-and 3-amino-8-methyl-8H-quino[4,3,2-kl]acridine and 8,13-dimethyl-8H-quino[4,3,2-kl]acridinium salts
I Hutchinson et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2004)
Biological activity of the G-quadruplex ligand RHPS4 (3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate) is associated with telomere capping alteration
C Leonetti et al.
MOLECULAR PHARMACOLOGY (2004)
Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat
E Gavathiotis et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
DNA damage foci at dysfunctional telomeres
H Takai et al.
CURRENT BIOLOGY (2003)
POT1 as a terminal transducer of TRF1 telomere length control
D Loayza et al.
NATURE (2003)