Journal
JOURNAL OF ESSENTIAL OIL RESEARCH
Volume 22, Issue 3, Pages 263-269Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/10412905.2010.9700321
Keywords
Terpene alcohol; antibacterial activity; aliphatic carbon chain; Staphylococcus aureus
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The antibacterial activities against Staphylococcus aureus of terpene alcohols with aliphatic carbon chains of various lengths were investigated. Farnesol and nerolidol, which each contain two isoprene units, had the strongest antibacterial activities and damaging effects on cell membranes of all the terpene alcohols tested. Plaunotol, which is a diterpene, had antibacterial activity similar to that of sesquiterpenes. The relationship between the length of the carbon chain bonded to the hydroxyl group and activity suggests that the length of the carbon chain is an important determinant of antibacterial activity and cell membrane-damaging activity. It was concluded that the carbon chain length of C10-C12 was appropriate to show the activity.
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