Journal
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Volume 24, Issue 5, Pages 1128-1132Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14756360802667688
Keywords
Galinsoga parviflora; Galinsoside A; Galinsoside B; Antioxidant activity; Enzyme inhibition; Urease; alpha-glucosidase
Funding
- Higher Education Commission of Pakistan
- International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi
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Galinsosides A (1) and B (2), new flavanone glucosides together with two known flavanones, 7,3',4'-trihydroxyflavanone (3) and 3,5,7,3',4'-pentahydroxyflavanone (4) have been isolated from an ethyl acetate-soluble fraction of Galinsoga parviflora. Their structures were assigned on the basis of spectral studies. Compound 1 showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active. On the other hand, 2 showed inhibitory potential against alpha-glucosidase.
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