Journal
OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA
Volume 42, Issue 1, Pages 135-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ogc.2014.10.003
Keywords
Progesterone; Luteal phase; Luteal phase deficiency; Luteal phase support; ART
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Funding
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [R01HD067721] Funding Source: NIH RePORTER
- NICHD NIH HHS [R01 HD067721] Funding Source: Medline
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Progesterone production from the corpus luteum is critical for natural reproduction. Progesterone supplementation seems to be an important aspect of any assisted reproductive technology treatment. Luteal phase deficiency in natural cycles is a plausible cause of infertility and pregnancy loss, though there is no adequate diagnostic test. This article describes the normal luteal phase of the menstrual cycle, investigates the controversy surrounding luteal phase deficiency, and presents the current literature for progesterone supplementation during assisted reproductive technologies.
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