Journal
JOURNAL OF ENDODONTICS
Volume 44, Issue 10, Pages 1553-1557Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.joen.2018.06.016
Keywords
Dental cements; Enterococcus faecalis; modified direct contact test; nanoparticles; quaternary ammonium
Categories
Funding
- Foundation for Endodontics [1500596]
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Introduction: The purpose of this study was to investigate the physical and antibacterial properties of a resin sealer mixed with a quaternary ammonium compound, dimethylaminododecyl methacrylate (DMAHDM) and nanosilver (NAg). Methods: A pilot study was completed to determine the highest concentrations of DMAHDM and NAg that did not significantly alter the physical properties (setting time, flow, solubility, and dimensional change) of AH Plus (Dentsply Sirona, York, PA) when added to the sealer. These concentrations were selected to create a modified resin sealer (mAH Plus). A modified direct contact test evaluated antibacterial properties of AH Plus, DMAHDM + AH Plus, NAg + AH Plus, and mAH Plus at days 1, 7, and 14 against Enterococcus faecalis. Results: Concentrations of 2.5% DMAHDM and 0.15% NAg were added to AH Plus. The flow of mAH Plus was significantly decreased but still within American National Standards Institute/American Dental Association specifications. There were no significant differences in setting time, solubility, or dimensional change. On day 1, 0.15% NAg + AH Plus, 2.5% DMAHDM + AH Plus, and mAH Plus were significantly more effective against E. faecalis compared with AH Plus (P < .05). On days 7 through 14, 2.5% DMAHDM + AH Plus and mAH Plus continued to be significantly more antibacterial than AH Plus (P < .05). Conclusions: The addition of 0.15% NAg and 2.5% DMAHDM did not adversely affect the physical properties of AH Plus, and mAH Plus was significantly more antibacterial against E. faecalis.
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