4.5 Article

Listeriolysin O enhances cytoplasmic delivery by Her-2 targeting liposomes

Journal

JOURNAL OF DRUG TARGETING
Volume 18, Issue 4, Pages 313-320

Publisher

INFORMA HEALTHCARE
DOI: 10.3109/10611861003663549

Keywords

Cancer; controlled drug delivery; immunoliposomes; Her-2; ErbB2; trastuzumab; listeriolysin O; thermosensitive liposomes; Herceptin (c)

Funding

  1. Alaska Run for Women
  2. Alaska Men's Run
  3. University of Alaska Anchorage

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To enhance cytoplasmic delivery of liposomal contents to breast cancer cells, the authors have attached the pore-forming protein, listeriolysin O (LLO), to thermosensitive liposomes. The antibody trastuzumab (Herceptin

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