Journal
JOURNAL OF DIGESTIVE DISEASES
Volume 14, Issue 11, Pages 579-586Publisher
WILEY-BLACKWELL
DOI: 10.1111/1751-2980.12086
Keywords
diagnosis; Helicobacter pylori; high definition endoscopy; i-scan; magnifying endoscopy
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Funding
- Clinical Projects of the Ministry of Health of China
- Taishan Scholar Program of Shandong Province
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ObjectiveThis study aimed to compare the diagnostic value and image quality of high-definition magnifying white light endoscopy (M-WLE) and high-definition magnifying endoscopy with i-scan (M-i-scan) for Helicobacter pylori (H.pylori) infection. MethodsPatients complaining of dyspepsia who underwent esophagogastroduodenoscopy at the Endoscopy Unit of Qilu Hospital (Jinan, Shandong Province, China) from January to March, 2011 were prospectively recruited. The greater curvature of the stomach was carefully observed using both M-WLE and M-i-scan. The gastric mucosal classification and image quality scores were recorded. The relationship between gastric mucosal classification and final diagnosis of H.pylori infection was determined. ResultsA total of 84 patients were recruited in this study. The accuracy and specificity of the combination of types 2-3 patterns predicting H.pylori infection were significantly higher for M-i-scan than those for M-WLE (accuracy: 94.0% vs 84.5%, P=0.046; and specificity: 93.5% vs 80.6%, P=0.032), while the sensitivity of the two modes was the same. The M-i-scan provided a better image quality for H.pylori infection than M-WLE (P<0.001). ConclusionThe M-i-scan may be superior to M-WLE for the prediction of H.pylori infection, but its diagnostic sensitivity needs to be improved.
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