Journal
JOURNAL OF DERMATOLOGICAL TREATMENT
Volume 26, Issue 1, Pages 59-62Publisher
INFORMA HEALTHCARE
DOI: 10.3109/09546634.2013.869301
Keywords
Propranolol; treatment; vascular malformation
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The beta-blocker propranolol has become a valuable and effective drug for the treatment of infantile hemangiomas. Its therapeutic action probably results from vasoconstriction, blocking of angiogenesis through effects on vascular endothelial growth factor and induction of apoptosis. It is reasonable to suggest that propranolol can also be used effectively in the treatment of other vascular abnormalities. This case report describes propranolol treatment of vascular malformations such as Klippel-Trenaunay syndrome or Parkes-Weber syndrome in adults.
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