Journal
JOURNAL OF DENTAL RESEARCH
Volume 89, Issue 1, Pages 19-28Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0022034509351969
Keywords
dental nanocomposite; nanoparticles; strength; Ca and PO4 ion release; fluoride release; tooth caries inhibition
Categories
Funding
- NIH [R01 DE14190, R01 DE17974, R01 DE16416]
- Maryland Nano-Biotechnology Initiative Award
- University of Maryland Dental School in Baltimore
- NIST
- ADAF
- NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH [R01DE014190] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH [R01DE016416, R01DE017974] Funding Source: NIH RePORTER
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This article reviews recent studies on: (1) the synthesis of novel calcium phosphate and calcium fluoride nanoparticles and their incorporation into dental resins to develop nanocomposites; (2) the effects of key microstructural parameters on Ca, PO4, and F ion release from nanocomposites, including the effects of nanofiller volume fraction, particle size, and silanization; and (3) mechanical properties of nanocomposites, including water-aging effects, flexural strength, fracture toughness, and three-body wear. This article demonstrates that a major advantage of using the new nanoparticles is that high levels of Ca, PO4, and F release can be achieved at low filler levels in the resin, because of the high surface areas of the nanoparticles. This leaves room in the resin for substantial reinforcement fillers. The combination of releasing nanofillers with stable and strong reinforcing fillers is promising to yield a nanocomposite with both stress-bearing and caries-inhibiting capabilities, a combination not yet available in current materials.
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