Journal
JOURNAL OF DAIRY RESEARCH
Volume 78, Issue 4, Pages 471-478Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0022029911000628
Keywords
Camel milk; casein; proteolysis; ACE; antioxidant
Funding
- Research Council of the University of Tehran
- Iran National Science Foundation (INSF)
- Center for International Research and Collaboration (ISMO)
- French Embassy in Tehran
- French Ministry of Foreign Affairs
- Gundishapur project [18647RM]
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The aim of this study was to investigate the effects of enzymatic hydrolysis with digestive enzymes of camel whole casein and beta-casein (beta-CN) on their antioxidant and Angiotensin Converting Enzyme (ACE)-inhibitory properties. Peptides in each hydrolysate were fractionated with ultrafiltration membranes. The antioxidant activity was determined using a Trolox equivalent antioxidant capacity (TEAC) scale. After enzymatic hydrolysis, both antioxidant and ACE-inhibitory activities of camel whole casein and camel beta-CN were enhanced. Camel whole casein and beta-CN showed significant ACE-inhibitory activities after hydrolysis with pepsin alone and after pepsinolysis followed by trypsinolysis and chymotrypsinolysis. Camel beta-CN showed high antioxidant activity after hydrolysis with chymotrypsin. The results of this study suggest that when camel milk is consumed and digested, the produced peptides start to act as natural antioxidants and ACE-inhibitors.
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