Journal
JOURNAL OF CROHNS & COLITIS
Volume 4, Issue 5, Pages 603-605Publisher
OXFORD UNIV PRESS
DOI: 10.1016/j.crohns.2010.05.001
Keywords
Infliximab; Crohn s; BCG; Pregnancy; Vaccination
Categories
Ask authors/readers for more resources
We present the case of a 28 year old lady with refractory Crohn s Disease treated with infliximab throughout her pregnancy Her baby was born healthy and received a Bacillus Calmette Guerin (BCG) vaccine aged 3 months Soon after this the infant became unwell and died aged 4 5 months At post mortem the cause of death was attributed to an unusual complication of the BCG vaccine, known as disseminated BCG BCG vaccination is contraindicated in individuals who are receiving immunosuppressive drugs We recommend physicians should exercise caution before such vaccines are used in infants born to mothers taking anti TNF therapies or other potentially immunosuppressive IgG1 antibodies (C) 2010 European Crohns and Colitis Organisation Published by Elsevier B V All rights reserved
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available