Journal
JOURNAL OF CROHNS & COLITIS
Volume 4, Issue 4, Pages 390-397Publisher
OXFORD UNIV PRESS
DOI: 10.1016/j.crohns.2010.03.008
Keywords
Inflammatory bowel disease (IBD); Crohn's disease; Ulcerative colitis; Pulmonary manifestations; 5-ASA
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Inflammatory bowel disease (IBD) is associated with a number of extraintestinal manifestations that may involve most organ systems. Extraintestinal manifestations are more common in Crohn disease (CD) and may include rheumatologic, ocular, dermatologic, biliary and pulmonary manifestations. The most common pulmonary manifestations of IBD are drug-induced lung disease. Other manifestations include parenchymal disease, pleuritis and overlap syndromes. We present a case series of 7 patients with non-infectious pulmonary manifestations of IBD, which included cryptogenic organizing pneumonia, usual interstitial pneumonitis (UIP), Langerhans granulomatosis, and eosinophilic pneumonia. Concurrent extraintestinal manifestations present in these patients included arthralgia, iritis, and pyoderma gangrenosum. In most patients the development of pulmonary disease parallels that of the intestinal disease activity, extraintestinal manifestations and concurrent use of 5-ASA medications. (C) 2010 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.
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