Pressure ulcer incidence and risk factors in ventilated intensive care patients

Purpose: The aim of this study was to determine the incidence of pressure ulcers (PUs) in ventilated patients in all intensive care units (ICUs) in Granada (Spain) and identify risk factors for their development. Materials and Methods: A prospective cohort study in 9 medical-surgical ICUs was conducted. Two hundred ninety-nine patients with more than 24 hours on mechanical ventilation (MV) were enrolled during 2 periods in a 5-month study. Pressure ulcers of patients were measured according to the European Pressure Ulcer Advisory Panel. Results: Of the 299 patients initially enrolled, 47 (16%) developed PUs of at least grade IT severity. The incidence density of PUs was 13.4 cases per 1000 patient-days of ICU stay and 19.6 cases per 1000 patient-days on MV. Logistic regression identified first-day respiratory sequential organ failure assessment (odds ratio [OR], 1.56; 95% confidence interval [CI], 1.026-2.360; P=.037), fourth-day cardiovascular sequential organ failure assessment (OR, 1.33; 95% Cl, 1.066-1.664; P=.012), age (OR, 1.042; 95% CI, 1.013-1.072; P=.004), winter period (OR, 4.60; 95% Cl, 1.99-10.59; P<.001), and length of MV before PUs (OR, 1.042; 95% Cl, 1.005-1.080; P=.024) as significant independent predictors of PU development. Conclusions: Among other factors previously known in ventilated patients, duration of MV and winter period were identified as risk factors for PUs. (C) 2010 Elsevier Inc. All rights reserved.