Journal
JOURNAL OF CRANIOFACIAL SURGERY
Volume 25, Issue 1, Pages 21-25Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.scs.0000436743.75289.6b
Keywords
Facial reconstruction; prefabricated flaps; stem cell therapy
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Funding
- National Natural Science Foundation of China [30925034, 81101437]
- National Key Project of Scientific and Technical Supporting Programs - Ministry of Science & Technology of China [2012BAI11B03]
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Total face skin and soft-tissue defects remain one of the biggest challenges in reconstructive surgery. Reconstruction of the entire face with uniform coverage and delicate features is difficult to achieve. To avoid the patchwork result seen in multiple flaps and skin grafts, 1 monoblock flap that has similar color, texture, and thickness might be an ideal option to minimize the incisional scars and several surgical procedures but is unavailable with current approaches because of the lack of sufficient matched tissue and the unreliable blood supply for such a large flap. To acquire a monoblock flap for full face reconstruction, we combine the prefabricated flaps, skin overexpansion, and bone marrow mononuclear stem cell transplantation for total facial resurfacing. In this article, we present our experience from our case series that provides universally matched skin and near-normal facial contour. It is a reliable and an excellent reconstructive option for massive facial skin defect.
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