Journal
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
Volume 42, Issue 4, Pages E47-E50Publisher
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.jcms.2013.05.029
Keywords
Dental implant; Bio-Oss (R); Platelet-rich fibrin; Bone graft; Maxillary sinus
Categories
Funding
- Korea Health technology R&D Project, Ministry of Health & Welfare, Republic of Korea [A100054]
- Korea Health Promotion Institute [A100054] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Anorganic bovine bone (Bio-Oss (R)) particles are one of the most popular grafting materials. The particles are often mixed with platelet-rich fibrin (PRF) or a commercial fibrin (Tisseel (R)) to form a mouldable graft material. The objective of this study was to compare the potentials of PRF-mixed Bio-Oss (R) and Tisseel (R) mixed Bio-Oss (R) to enhance bone regeneration in a canine sinus model. Six mongrel dogs were used in this study. After elevating the sinus membrane in both maxillary sinus cavities, an implant was placed into the sinus cavity. In one of the sinus cavities, the PRF/Bio-Oss (R) composite was grafted, and the Tisseel (R)/Bio-Oss (R) composite was grafted in the other sinus cavity. After a 6 month healing period, bone formation in the graft sites and bone-implant contact were evaluated. The mean osseointegration rate was 43.5 +/- 12.4% and new bone formation rate 41.8 +/- 5.9% in the PRF/Bio-Oss (R) composite sites. In the Tisseel (R)/Bio-Oss (R) composite sites they were 30.7 +/- 7.9% and 31.3 +/- 6.4%. There were statistically significant differences between the groups. The findings from this study suggest that when platelet-rich fibrin is used as an adjunct to Bio-Oss (R) particles for bone augmentation in the maxillary sinus, bone formation in the graft sites is significantly greater than when Tisseel (R) is used. (C) 2013 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
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