Journal
JOURNAL OF COORDINATION CHEMISTRY
Volume 63, Issue 21, Pages 3706-3713Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/00958972.2010.517268
Keywords
Schiff base; Molecular docking; Urease; Inhibitor
Categories
Funding
- National Natural Science Foundation of Hubei Province, P.R. China [2009CDA022]
Ask authors/readers for more resources
A Ni(II) Schiff-base complex, Ni(C14H10NOBr2)2, was synthesized and structurally characterized by single-crystal X-ray analysis. Its inhibitory activity against Helicobacter pylori urease was evaluated in vitro and showed strong inhibitory activity against H. pylori urease compared with acetohydroxamic acid (IC50 = 42.12 mu mol L-1), which is a positive reference. A docking analysis using the autodock 4.0 program could explain the inhibitory activity of the complex against urease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
