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Biofunctional nanosystems based on dendritic polymers

Journal

JOURNAL OF CONTROLLED RELEASE
Volume 161, Issue 2, Pages 484-495

Publisher

ELSEVIER
DOI: 10.1016/j.jconrel.2011.12.040

Keywords

Dendritic polymers; Nanomedicine; Drug delivery; Gene delivery; Targeting; Polycationic and polyanionic dendritic architectures

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Among the various polymeric architectures, dendritic polymers have received a substantial scientific focus for their highly branched, multifunctional, and well-defined structures. Dendritic scaffolds have found many applications for designing nanoscale drug/gene delivery carriers and constructing diagnostic and biosensor devices, and protein-resistant surfaces. A significant number of research groups across Europe share the common objective, yet in conspicuously individual ways, of utilizing such polymers for devising innovative biomedical tools and techniques. This review describes the European effort of finding the application of dendritic polymers as advanced generation therapeutics within the purview of nanomedicine. (c) 2012 Elsevier B.V. All rights reserved.

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