Journal
JOURNAL OF CONTROLLED RELEASE
Volume 161, Issue 1, Pages 62-72Publisher
ELSEVIER
DOI: 10.1016/j.jconrel.2012.04.032
Keywords
Microemulsion; NMR; Pharmaceutical; Diffusion coefficient; Relaxation
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Microemulsions have successfully proven themselves as useful vehicles for drugs through the different routes of administration because they can confer on drugs greater water solubility and bioavailability. The ability to understand the structural aspects of these important drug delivery systems is essential to the progress of this science. The use of NMR techniques in pharmaceutical and drug delivery science is increasing especially in the characterization field. This review demonstrates the major and novel NMR methods and techniques used in understanding and characterizing the different microemulsion components, types and structures. (C) 2012 Elsevier B.V. All rights reserved.
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