4.4 Article

CANADA: Designing Nucleic Acid Sequences for Nanobiotechnology Applications

Journal

JOURNAL OF COMPUTATIONAL CHEMISTRY
Volume 31, Issue 3, Pages 660-663

Publisher

JOHN WILEY & SONS INC
DOI: 10.1002/jcc.21353

Keywords

CANADA; DNA computing; nanobiotechnology; DNA sequence design; specific hybridization

Funding

  1. European Union [013775]
  2. Zentrum fur Angewandte Chemische Genomik
  3. Deutsche Forschungsgemeinschaft [FE 943/1-1]

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The design of nucleic acid sequences for a highly specific and efficient hybridization is a crucial step in DNA computing and DNA-based nanotechnology applications. The CANADA package contains software tools for designing DNA sequences that meet these and other requirements. as well as for analyzing and handling sequences. CANADA is freely available, including a detailed manual and example input files, at http://ls11-www.cs.unidortmund.de/molcomp/downloads. (C) 2009 Wiley Periodicals, Inc. J Comput Chem 31: 660-663, 2010

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