Journal
JOURNAL OF COMBINATORIAL CHEMISTRY
Volume 12, Issue 5, Pages 659-663Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cc100064c
Keywords
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Funding
- National Natural Science Foundation of China [20672079, 20910102041]
- Natural Science Foundation of Jiangsu Province [BK 2006048]
- Nature Science Key Basic Research of Jiangsu Province for Higher Education [06KJ A15007]
- Specialized Research Fund for the Doctoral Program of Higher Education [20060285001]
- Soochow University
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A simple and efficient approach to the synthesis of a novel series of polysubstituted 6'-(1H-indol-3-yl)-1',7'-dihydrospiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-2-one derivatives in high yields was developed from a one-pot, three-component reaction of 3-cyanoacetyl indoles, isatins, and 1H-pyrazol-5-amines in H(2)O/HOAc.
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