Journal
JOURNAL OF COMBINATORIAL CHEMISTRY
Volume 12, Issue 4, Pages 430-434Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cc100003c
Keywords
-
Funding
- Foundation of Key Laboratory of Organic Synthesis of Jiangsu Province
Ask authors/readers for more resources
A series of 4-aza-podophyllotoxin derivatives have been synthesized regioselectively via the three-component reaction of aldehydes, aromatic amines, and tetronic acid catalyzed by L-proline. This method has the advantages of high yield, high regioselectivity, extensive adaptability, easy operation, and environmental friendliness. These compounds were also investigated in vitro, and sonic were found to have good anticancer activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available