Journal
JOURNAL OF COMBINATORIAL CHEMISTRY
Volume 12, Issue 1, Pages 186-190Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cc900125a
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Funding
- Research Council of Shahid Beheshti University
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In this work, two novel isocyanide-based multicomponent reactions of 1,2-diamine compounds with diketene have been developed as efficient strategies for the synthesis of 2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-2-carboxamides with regiochemical control and 1,6-dihydropyrazine-2,3-dicarbonitriles in good to excellent yields at ambient temperature.
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